Life Sciences is an international journal publishing articles that emphasize the molecular, cellular, and functional basis of therapy. The journal emphasizes the understanding of mechanism that is relevant to all aspects of human disease and translation to patients. All articles are rigorously reviewed.

 

The Journal favors publication of full-length papers where modern scientific technologies are used to explain molecular, cellular and physiological mechanisms. Articles that merely report observations are rarely accepted. Recommendations from the Declaration of Helsinki or NIH guidelines for care and use of laboratory animals must be adhered to. Articles should be written at a level accessible to readers who are non-specialists in the topic of the article themselves, but who are interested in the research. The Journal welcomes reviews on topics of wide interest to investigators in the life sciences. We particularly encourage submission of brief, focused reviews containing high-quality artwork and require the use of mechanistic summary diagrams.

 

Manuscripts should present novel preclinical findings addressing questions of biological significance to human disease. Studies that fail to do so may be rejected without review. Quantitative conclusions must be based on truly quantitative methods. Life Sciences does not publish work on the actions of biological extracts of unknown chemical composition. Compounds studied must be of known chemical structure and concentration. The study must be reproducible; materials used must be available to other researchers so they can repeat the experiment. Clinical studies may be considered if they expand understanding of mechanism, but the journal does not encourage clinical trial reports.

 

生命科学是一本国际期刊，发表文章强调治疗的分子，细胞和功能基础。该杂志强调了对与人类疾病各个方面以及对患者的翻译相关的机制的理解。所有文章均经过严格审查。

 

该杂志偏爱发表全文，其中使用现代科学技术来解释分子，细胞和生理机制。仅报告观察结果的文章很少被接受。必须遵守《赫尔辛基宣言》或NIH关于护理和使用实验动物的准则的建议。文章的撰写水平应适合那些不是文章主题本身的非专家但对研究感兴趣的读者。该期刊欢迎对生命科学领域的研究人员感兴趣的主题进行评论。我们特别鼓励提交简短，集中的评论，其中应包含高质量的艺术品，并要求使用机械汇总图。

 

手稿应提供新颖的临床前发现，以解决对人类疾病具有生物学意义的问题。没有这样做的研究可能会被拒绝，而不会进行审查。定量结论必须基于真正的定量方法。生命科学不会发表有关化学成分未知的生物提取物的作用的工作。研究的化合物必须具有已知的化学结构和浓度。该研究必须可重复；使用的材料必须可供其他研究人员使用，以便他们可以重复实验。如果可以扩大对机制的了解，可以考虑进行临床研究，但该期刊不鼓励临床试验报告。