Chemico-Biological Interactions publishes research reports and review articles that examine the molecular, cellular, and/or biochemical basis of toxicologically relevant outcomes. Special emphasis is placed on toxicological mechanisms associated with interactions between chemicals and biological systems. Outcomes may include all traditional endpoints caused by synthetic or naturally occurring chemicals, both in vivo and in vitro. Endpoints of interest include, but are not limited to carcinogenesis, mutagenesis, respiratory toxicology, neurotoxicology, reproductive and developmental toxicology, and immunotoxicology.

 

CBI discourages papers that are descriptive in nature and that do not address toxicological mechanisms (e.g., reports of toxicological effects following chemical exposure in absence of mechanistic experiments). CBI also discourages papers reporting on toxicological effects from materials, such as plant extracts or herbal medicines, that have not been chemically characterized.

 

 

化学-生物相互作用发表研究报告和评论文章，以检查毒理学相关结果的分子，细胞和/或生化基础。特别强调与化学物质和生物系统之间的相互作用有关的毒理学机制。结果可能包括体内或体外由合成或天然化学物质引起的所有传统终点。感兴趣的终点包括但不限于致癌，诱变，呼吸道毒理学，神经毒理学，生殖和发育毒理学和免疫毒理学。

 

CBI不鼓励使用本质上具有描述性且未解决毒理学机理的论文（例如，在没有机械实验的情况下化学暴露后的毒理学影响报告）。CBI还不鼓励发表报道，报道未经化学表征的材料（如植物提取物或草药）的毒理作用。